http://www.cancerindex.org/geneweb//FCGR2A.htm WebNM_001136219.3(FCGR2A):c.281C>T (p.Ala94Val) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Dec 21, 2024) Review status: 1 star out of maximum of 4 stars
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WebFCGR2A is a cell surface receptor that was formerly known as CD32. The gene locus is at 1q23; the gene product is expressed on a wide variety of cell types, and it mediates multiple cell-type specific functions including phagocytosis, release of inflammatory mediators, and clearance of immune complexes (76). WebAntibodies that detect CD16/CD32 can be used in several scientific applications, including Flow Cytometry, ELISA, Functional assay, Immunohistochemistry and Immunoprecipitation. These antibodies target CD16/CD32 in Mouse and Rhesus Monkey samples. Our CD16/CD32 monoclonal, polyclonal and recombinant monoclonal antibodies are …
WebBrand: BD Pharmingen™ Alternative Name: CD32a,FcγRIIa, FCGR2A; CD32b, FcγRIIb, FCGR2B; CD32c, FcγRIIc, FCGR2C Reactivity: Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development) … WebBinds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes …
WebFCGR2A single nucleotide polymorphism confers susceptibility to childhood-onset idiopathic nephrotic syndrome Childhood-onset idiopathic nephrotic syndrome affects 1.15-3.4 children/100,000 children/year in Western Countries. Immune-mediated mechanisms, particularly T cell-mediated, are thought to play a key pathogenic role. WebApr 10, 2024 · The FCGR2a receptor was genotyped for each sample, and RNA-seq was performed on isolated, leukocyte-depleted platelets. Transcriptomic data were used to create a modular landscape to explore the differences between SLE patients and controls and various clinical parameters in the context of FCGR2a genotypes.
WebFcgamma Receptor IIa (FCGR2A) Polymorphism Is Associated With Severe Respiratory Syncytial Virus Disease in Argentinian Infants. Susceptibility to Plasmodium falciparum …
WebNov 5, 2015 · The CD32a immunoglobulin G (IgG) receptor (Fcγ receptor IIa) is a potential therapeutic target for diseases in which IgG immune complexes (ICs) mediate inflammation, such as heparin-induced thrombocytopenia, rheumatoid arthritis, and systemic lupus erythematosus. Monoclonal antibodies (mAbs) are a promising strategy for treating such … port of hamilton canada mapWebFCGR2A; Fc fragment of IgG receptor IIa. Aliases: CD32, FCG2, FcGR, CD32A, CDw32, FCGR2, IGFR2, FCGR2A1. Location: 1q23.3. Summary: This gene encodes one … port of harlem magazineWebAug 1, 2010 · The FcγRI is a high-affinity receptor that mainly binds monomeric IgG, while FcγRII and FcγRIII interact preferentially with immune complexes 4, 5, 6, 7. Following ligand binding, FcγRI, FcγRIIa, and FcγRIII are activating receptors while FcγRIIb is the only inhibitory receptor. port of hanstholmWeb2 days ago · RG2A Russia. Login is required for additional detail. QSL: 115470, Russia, Moscow, p.o.box 19 Email: Login required to view Ham Member Lookups: 30091 iron finishWebThe FCGR2a receptor was genotyped for each sample, and RNA-seq was performed on isolated, leukocyte-depleted platelets. Transcriptomic data were used to create a … port of hanjin• FCGR2A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) This article incorporates text from the United States National Library of Medicine, which is in the public … port of hampton roads vaWebNM_001136219.3(FCGR2A):c.776T>C (p.Phe259Ser) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Dec 1, 2024) Review status: 1 star out of maximum of 4 stars iron fire bar and grill walker mn